Cyclooxygenasen.环氧化酶
Protonn.质子
PatientswithbleedingulcersduetoNSAIDsotherthanlow-doseaspirinshoulddiscontinueNSAIDs;ifNSAIDsmustberesumed,acyclooxygenase-2(COX-2)–selectiveNSAIDplusaproton-pumpinhibitorshouldbeused.Patientswithbleedingulcersduetolow-doseaspirintakenforsecondarycardiovascularpreventionshouldresumetheuseofaspirinwithin1to7daysafterbleedingstops.1
因非甾体抗炎药物而非低剂量阿司匹林引起溃疡出血的患者,应停止使用非甾体类抗炎药物;如果需要重新开始服用非甾体类抗炎药物,应使用环氧化酶-2选择性非甾体抗炎药加质子泵抑制剂。因心血管二级预防服用低剂量阿司匹林而引起溃疡出血的患者,在出血停止后的1-7天内应该重新开始服用阿司匹林。
1.常用医学词组
proton-pumpinhibitor质子泵抑制剂
nonsteroidalantiinflammatorydrugs(NSAIDs)非甾体抗炎药物
消化性溃疡Pepticulcers
cyclooxygenase-2(COX-2)–selectiveNSAID
环氧化酶-2选择性非甾体抗炎药
secondarycardiovascularprevention
心血管二级预防
他汀类药物Statins
Inrecentdecades,themainulceraetiologyhasshiftedinmanycountriesfromHelicobacterpyloritonon-steroidalanti-inflammatorydrugs(NSAIDs),includingaspirin.Useofotherdrugssuchassteroids,aldosteroneantagonists,andselectiveserotoninreuptakeinhibitorscancontributetogastroduodenalulcerationandits
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